Detalhe da pesquisa
1.
Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis.
Gastroenterology
; 166(5): 842-858.e5, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38154529
2.
Chemokine-mucinome interplay in shaping the heterogeneous tumor microenvironment of pancreatic cancer.
Semin Cancer Biol
; 86(Pt 2): 511-520, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35346803
3.
Mucin 5AC Serves as the Nexus for ß-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance.
Gastroenterology
; 162(1): 253-268.e13, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34534538
4.
Malondialdehyde-Acetaldehyde Extracellular Matrix Protein Adducts Attenuate Unfolded Protein Response During Alcohol and Smoking-Induced Pancreatitis.
Gastroenterology
; 163(4): 1064-1078.e10, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35788346
5.
Mucins reprogram stemness, metabolism and promote chemoresistance during cancer progression.
Cancer Metastasis Rev
; 40(2): 575-588, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33813658
6.
Unraveling mucin domains in cancer and metastasis: when protectors become predators.
Cancer Metastasis Rev
; 39(3): 647-659, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32488403
7.
RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3.
Gastroenterology
; 159(5): 1898-1915.e6, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781084
8.
Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1.
Gastroenterology
; 155(3): 892-908.e6, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29864419
9.
Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells.
BMC Cancer
; 18(1): 1157, 2018 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30466404
10.
Lupeol evokes anticancer effects in oral squamous cell carcinoma by inhibiting oncogenic EGFR pathway.
Mol Cell Biochem
; 417(1-2): 97-110, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27206736
11.
Connectivity mapping-based identification of pharmacological inhibitor targeting HDAC6 in aggressive pancreatic ductal adenocarcinoma.
NPJ Precis Oncol
; 8(1): 66, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38454151
12.
Elevated PAF1-RAD52 axis confers chemoresistance to human cancers.
Cell Rep
; 42(2): 112043, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36709426
13.
Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies.
NPJ Precis Oncol
; 7(1): 74, 2023 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567918
14.
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer.
Cell Death Dis
; 13(10): 839, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36180487
15.
Small molecule inhibitor against onco-mucins disrupts Src/FosL1 axis to enhance gemcitabine efficacy in pancreatic ductal adenocarcinoma.
Cancer Lett
; 551: 215922, 2022 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36285687
16.
MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion.
Mol Cancer Res
; 20(8): 1208-1221, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35533267
17.
Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma.
Oncogene
; 41(48): 5147-5159, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36271032
18.
Recent advances in organoid development and applications in disease modeling.
Biochim Biophys Acta Rev Cancer
; 1875(2): 188527, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33640383
19.
The Current Landscape of Antibody-based Therapies in Solid Malignancies.
Theranostics
; 11(3): 1493-1512, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33391547
20.
PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor Lesions.
Clin Cancer Res
; 27(19): 5415-5429, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172498